Chronic venous disease progression and modification of predisposing factors
Kostas TI, Ioannou CV, Drygiannakis I, Georgakarakos E, Kounos C, Tsetis D, Katsamouris AN. J Vasc Surg. 2010;51:900-907. Aim: The aim of this study was to evaluate long-term characteristics of chronic venous disease (CVD) progression and its correlation with the modification of specific risk factors. Methods: In this prospective, follow-up study, the contralateral limb of 73 patients (95% women; mean age, 48±12 years) undergoing varicose vein surgery were prospectively evaluated using physical and color duplex examination and were classified using the Clinical, Etiological, Anatomical, and Pathological (CEAP) classification. After 5 years of follow-up, the development of new sites of reflux…