Management of chronic venous disease: the example of MPFF at a dose of 500 mg
Albert Adrien RAMELET Lausanne, Switzerland ABSTRACT Chronic venous disease (CVD) is a common condition and represents a spectrum of disorders. The CEAP classification has been adopted worldwide to facilitate meaningful communication about the disease and to serve as a basis for more scientific analysis of treatment options. In addition to improved methods of defining CVD, there is also now increased understanding of the pathological processes involved in its development. Leukocyte-endothelium interactions are one of the earliest pathophysiological mechanisms at work and appear to be important in many aspects of the disease. The sequence of leukocyte adhesion, endothelial interaction, activation, and…
