5. Glue
Glue.
K. Gibson
There are many opportunities to improve current treatments for varicose veins: eliminate need for tumescent anesthesia, eliminate the need for compression stockings, significantly reduce postprocedure pain and bruising, and improve current treatment closure rates to >90%. The VenaSeal Sapheon Closure system is a new device using cyanoacrylate adhesive to embolize the saphenous veins safely and effectively through a catheter and a dispenser gun. The catheter is engineered to be inert to adhesive and to not stick, and the dispenser gun is designed to deliver a precise amount of glue into the vein. A feasibility study, a European multicenter study (eSCOPE), has been done and a US pivotal study (VeClose) is ongoing. The results of the first study showed that the Venaseal sapheon closure system offers a tumescent-free solution for treating symptomatic venous reflux disease. The closure rate of this new device is very high (96.2% at 2 years) and similar to current treatment technologies. It is safe and postprocedure compression stockings are not mandatory. In the last study, the primary end point is to be noninferior to radiofrequency (RF) on great saphenous vein closure and the secondary end point is to be superior to RF in reducing postprocedural pain and bruising.
